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Cellular neuroscience is the study of neurons at a cellular level.
Following several local graded depolarizations of the membrane potential, the threshold of excitation is reached, voltage-gated sodium channels are activated, which leads to an influx of Na ions.
As Na ions enter the cell, the membrane potential is further depolarized, and more voltage-gated sodium channels are activated.
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The Hodgkin–Huxley model of an action potential in the squid giant axon has been the basis for much of the current understanding of the ionic bases of action potentials.This includes morphology and physiological properties of single neurons.Several techniques such as intracellular recording, patch-clamp, and voltage-clamp technique, pharmacology, confocal imaging, molecular biology, two photon laser scanning microscopy and Ca2 imaging have been used to study activity at the cellular level.Such a process is also known as a positive feedback loop.As the rising phase reaches its peak, voltage-gated Na channels are inactivated whereas voltage-gated K channels are activated, resulting in a net outward movement of K ions, which repolarizes the membrane potential towards the resting membrane potential.
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Thus, not all neurons correspond to the stereotypical motor neuron with dendrites and myelinated axons that conduct action potentials.